All issues > Volume 25(9); 1982

Original Article

J Korean Pediatr Soc. 1982;25(9):914-921. Published online September 30, 1982.

A prospective study on immunoglobulins and ESR in acute viral hepatitis patients.

Jong Wie Choi, Sung Seek Lee, Ki Sup Chung

¹Department of Pediatrics, Yonsei University College of Medicine, Seoul，Korea

Abstract

This study was carried out in 78 subjects of both sexes who were affected by acute viral hepatitis and admitted to Severance Hospital attached to Yonsei Medical College from Oct. 1980 to June. 1981. Hepatitis B markers, serum immunoglobulins and ESR were respectively examined in all patients. The results were as follows. 1. In all patients, regardless of positivity of HB markers, IgG, IgA and IgM levels were slightly increased than, normal mean, level. But the higher increase in. IgM level would have a been found in HBsAg-negative patients. 2. In patients under 3 years of age, the higher increase in. IgM level would have been, rather found in HBsAg-positive patients. The percentage of ESR above 10 mm/hr was 79.5% in HBsAg-negative patients and 51.3% in HBsAg-positive patients. The mean levels of ERS were respectively 15.47±6.11 mm/hr and 11.49±6.53 mm/hr and there were significant diffe- rence in two study groups (p<0.01). 4. There was the proportional correlation between serum IgM levels and ESR in HBsAg- negative patients (p<0.01). The patients with ESR of above 25 mm/hr and IgM level of over 250 mg% were all HBsAg-negative patients. After all, we found that the measurement of IgM level and ESR in HBsAg-negative hepa- titis should be useful in. epidemiological and clinical work as a marker to reinforce the inability to demonstrate HBsag.

Keywords :Immunoglobulins and ESR in Acute Viral Hepatitis Patients.