All issues > Volume 25(5); 1982

Original Article

J Korean Pediatr Soc. 1982;25(5):460-466. Published online May 31, 1982.

HLA Type in Bronchial Asthma and Atopic Dermatitis.

Ji Yoon Chung, Myung Sook Kim, Jung Ju Kim, Dong Hak Shin

¹Department of Pediatrics, Presbyterian Medical Center, College, of Medicine Keimyung University, Daegu, Korea.

Abstract

Since the histocompatibility was discovered, we have studied and determined many HLA types till the last workshop held in Los Angeles, USA, 1980. Nowadays we apply HLA types to organ transplantation, transfusion of blood, identification of paternity, study of ethnology and diagnosis of a specific disease. In the present study, 20 cases of bronchial asthma and 15 atopic dermatitis patients were selected. HLA types, serum IgE values and eosinophil count were analized and the data were compared with that of control group. The results were as follows: 1) Eosinophilia appeared in both bronchial asthma and atopic dermatitis 50% and 20% respectively. 2) The P-Values between the mean of serum IgE of bronchial asthma and control and atopic dermatitis and control were P<0.01 and P<0.05 respectively, which were statistically significant. 3) HLA type shows no statitically significant relationship between control group and bronchial asthma and atopic dermatitis.

Keywords :Bronchial asthma;Atopic dermatitis;HLA type