All issues > Volume 25(4); 1982

Case Report

J Korean Pediatr Soc. 1982;25(4):399-403. Published online April 30, 1982.

A Case of Disseminated Cryptococcosis with Skin Lesion and Miliary Shadows of the Lung.

Chan Ho Bang¹, Sang Keun Chi¹, In Ho Kim¹, Sang Woo Kim¹, Ill Hyang Ko²

¹Department of Pediatrics, Paik Hospital in Seoul, In-je Medical College, Korea.
²Department of Clinical Pathology, Paik Hospital in Seoul, In-je Medical College, Korea.

Abstract

A Case of disseminated cryptococcosis in a 5-year old girl is reported. Although twenty four pediatric cases of cryptococcosis were reported in Korea for the past 15years, this case's clinical picture is interesting and make diagnostic difficulties from miliary tuberculosis. She was transferred from a local clinic under the impression of miliary tuberculosis with chest X-ray showing miliary shadows. Mantoux test showed strong positive. She was not vaccinated BCG and had a history of contact with tuberculous patient for a month. Cough, fever and abdominal pain were persisted in spite of antituberculous medications(INH & RMP). CSF examination revealed cryptococcus cyst. Facial skin lesions which looked like Moluscum contagiosum at first became to be umbilicated and disseminated. It was diagtococcal lesions with little inflammatory response. In spite of treatment with 5-FC and Amphotericin B, her general condition became worse and died of respiratory failure. A brief review of the literature was done.

Keywords :Cryptococcosis;dissminated;Millary tuberculosis