All issues > Volume 24(12); 1981

Case Report

J Korean Pediatr Soc. 1981;24(12):1213-1217. Published online December 15, 1981.

A Case of Report of Letterer-Siwe Disease.

Nam Heon Kim¹, Jung Ho Lee¹, In Ho Kim¹, Churl Young Chung¹, Jong Eun Joo², Ill Hyang Ko²

¹Dept.of pediatrics, In-Je Medicial College, Seoul Korea
²Dept.of pathology, In-Je Medical College, Seoul Korea

Abstract

We experienced a cass of Letterer-Siwe disease in 2 month old infant. The patient was presented charateristic clinical findings such as hepatosplenomegaly, petechia, anemia, gene-ralized lymphadenopathy, and lung infiltration. The diagnosis was confirmed by lymphnode biopsy and bone marrow aspiration, which was compatible to Letterer-Siwe disease. A poor prognostic factor in Histiocytosis X is younger age (below 18 month), hepatospleno-megaly, anemia, bone marrow involvement, and hemorragic skin lesion. This patient was also poor prognostic victim as stated previously, because he was 2 month old and hepatosplenomegaly, anemia, pstechia, and bone marrow involvement.

Keywords :Histiocytosis X;Letterer-Siwe disease