All issues > Volume 23(12); 1980

Original Article

J Korean Pediatr Soc. 1980;23(12):1042-1047. Published online December 15, 1980.

Therapeutic Trial with Intravenous Human Sern Globulin and Antibiotics in Several Infections Diseases in Children.

I J Seol, W G Lee, S J Moon, C M Park

¹Department of Pediatrics, Hanyang University College of Medicine Seoul, Korea.

Abstract

We had comparative studies the effect of combined therapy of intravenous human immune serum globulin and antibiotics in the treatment of various infectious diseases from October 1979 to March 1980. The following results were obtained. 1. Total 37 cases including 24 male and 13 female and age distributions were from 1 month to 11 years of age. 2. Intravenous drip infusions were ranging 0.5gm (minimum) to 1.5gm (maximum) in total dose, with lOOmg/kg. 3. Most favorable effects (response) were observed to pertussis, hepatitis, mumps and measles, and less effective for pneumonia, sepsis, typhoid fever, and M.C.L.S. 4. None of the side effects or complications were observed in our study cases. 5. Prophylactic as well as therapeutic use of intravenous immune serum globulin are highly recommended for certain infections such as pertussis, hepatitis, measles, mumps, and bacterial infections combined with antibiotics.

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