All issues > Volume 23(10); 1980

Case Report

J Korean Pediatr Soc. 1980;23(10):833-842. Published online October 15, 1980.

Histiocytic Medullary Reticulosis in childhood Report of Three Cases.

Kwan Sub Chung¹, Kyo Sun Kim¹, Do Kwang Yun¹, Pyung Kil Kim¹, Kir Young Kim¹, Byung Soo Kim¹, Tae Jung Kwon², In Jun Chor²

¹Deptartment of Pediatirics and Yonsei University, Seoul, Korea.
²Department of pathology, College of Medicine, Yonsei Universty, Seoul, Korea.

Abstract

Three cases of hisiocytic medullary reticulosis occurring in children aged 6 years, 9 years and 14 years, are described. In all children the diagnosis was based on anemia, granulocytopenia, thrombocytopenia and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. They all showed immediate remission with combined chemotherapy of vinblastine and prednisolone, but Case 1 eventually died at 6 months after onset of this rapidly progressive, fatal illness and Case 2, 3 are alive 14 months after onset of their illness.

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