All issues > Volume 23(6); 1980

Original Article

J Korean Pediatr Soc. 1980;23(6):425-432. Published online June 15, 1980.

Comparison of Tuberculin Tests between Mono and Mantoux.

Hyung Kee Moon

¹Department of Pediatrics, College of Medicine Busan National University, Korea.

Abstract

To compare Mono-Test withstandard Mantoux tuberculin test, 221 primary school children aged 6 to 7, were randomly subjected. Each subject was simultaneously ted intradermally with three kinds of tuberculin reagents, 1TU PPD and 5TU PPD at one side of forearm and Mono-Test(Institut Merieux) at other side. Approximately 72 hours later, all sites of tested were measured by author. The criteria for positive Mantoux test was given when the tran sverse diameter of indr ation was 10mm or more. If 2mm or more induration was considreed as positive Mono-test, the sensitivity and specificity of Mono-Test to 1TU PPD Mantiux test were 94.44% and 75.14% respectively, ant those to 5TU PPD Mantoux test were 90.20% and 80.59% respectively. On the other hand, when 5mm or more induration was considered as positive Mono-Test, the sensitivity and specificity to 1TU PPD Mantoux test were 80.56% and 97.30% respectively and those to 5TU PPD Mantoux test were 66.67% and 98.24% respectively. Considering of false negativity and false positivity rates, Mono-Test be used only for screening of tuberculosis instead of Mantoux test and in that case it 4 will be better to using 2mm or more induration as a positive criteria of Mono-Test. Any doubtful or positive Mono-Test case sholud be retested with standard Mantoux test because of its relatively high falsespositive rates.

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