All issues > Volume 23(5); 1980

Case Report

J Korean Pediatr Soc. 1980;23(5):406-412. Published online May 15, 1980.

Two Cases of Rapidly Progressive Glomerulonphritis treated with pulse Methylprednisolone Therapy.

Soon Pyo Chung, Heung Kim, Kew Taek Kim

¹Department of Pediatrics, St. Benedict Hospital, Busan, Korea.

Abstract

Tow patients with severe glomerulonephitis and their serum creatinine clearance of 6.0ml/min/1.73m2 in case 2 were treated with high dosage intravenous methylprednisolone, 30mg/kg given over one hour period on each of six slternate days. Follwing the ?ulse therapy, both patients with rapidly deteriorathin renal funtion began to inprove and theit serum creatinine clearance levels showed over douvble by sixdays In both patients treated early in the curse of their disease, creatinine clearance increased to 80ml/min/1.73m2 in case 2 after one year follow-up and in recent study, clinical and laboratory findings are within normal limit.

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