All issues > Volume 23(4); 1980

Case Report

J Korean Pediatr Soc. 1980;23(4):321-325. Published online April 15, 1980.

A Case of Nephrotic Syndrome Associated with Distal Type Tubular Acidosis, Nephrocalcinosis and Renal Osteodystrophy.

Young Mo Sohn¹, Pyung Kil Kim¹, In Joon Choi², Chang Yun Park³

¹Department of Pediatrics, College of Medicine Yonsei University, Seoul, Korea.
²Department of Pathology, College of Medicine Yonsei University, Seoul, Korea.
³Department of Radiology, College of Medicine Yonset University, Seoul, Korea.

Abstract

A non-familial type nephrotic syndrome associated with distal renal tubual acidosis, nephrocalcinosis and renal osteodystropy is a very rare disease. A 4 year old boy was treated with prednisone under the impression of minimal lesion nephrotid syndrome but the response was not excellent along with persistant microhematuria in his serial urinalysis. Percutaneous renal biopsy speciman revealed microcalcification around afferent arteriols and peritubular area along with mild mesangial cell proliferations. Futher studies disclosed osteodystrophic change of the femurs. Patient had a typical forms of distal type renal tubular acidosis which was confirmed by NH4Cl and NaHCO3 loading tests. This case is the first cases of non-familial type nephrotic syndrome associated with nephrocalcinosis, renal osteodystrophy and distal RTA in Korea.

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