All issues > Volume 21(12); 1978

Original Article

J Korean Pediatr Soc. 1978;21(12):1125-1137. Published online December 31, 1978.

A clinicostatistical study of renal diseases in childhood.

C G Lee, H J Lee, H S Ahn, Y Choi, K W Ko

¹Department of Pediatrics, College of Medicine, Seoul National University, Korea.

Abstract

A clinicostatistical study was done on 282 cases of renal diseases which were admitted in the pediatric ward of S.N.U.H., during the 5 years from Jan. 1973 to Dec. 1977. The results were as follows. 1. During the 5 years, 282 cases of renal diseases were observed, which represents about 7.3% of total 3840 admitted cases during the same period. 2. Among the renal diseases in children, acute glomerulonephritis was the commonest renal disease showing 35.8% with 101 cases, and nephrotic syndrome (33.6%: 95 cases), chronic renal failure (7.4%:21 cases), acute pyelonephritis(4.2%:12cases) and others, in given order of frequency. (Table I -2) 3. The age distribution showed higher frequency in the age of 4~9 than that in the other age group. (Table I -3) 4. 36% of cases were noted in the autumn, 24% in the winter, 22% in the spring and 18% in the summer. 5. Fatal renal diseases were observed in 5 cases of chronic renal failure, 2 cases of nephrotic syndrome and 1 cases of polycystic kidney. 6. In acute glomerulonephritis, the highest incidence by age was noted 34.6% in the age groups of 7~9, and more than 80% of cases were observed in the autumn and the winter. Complications of acute glomerulonephritis were in the order of hypertensive encephalopathy (15 cases: 16.3%), congestive heart failure (9 cases: 9.8%) and acute renal failure(10 cases : 10.8%). 7. Among 25 cases of Henoch-Schonlein purpura which were observed during the same period, 10 cases (40%) showed renal involvement. 8. Among 12 cases of acute pyelonephritis, Escherichia coli was the commonest causative agent showing in 7 cases, which was sensitive to gentamycin and resistent to ampicillin in sensitivity test. 9. Among 5 cases of recurrent gross hematuria, percutaneous renal biopsy was performed in 4 cases. Histopathologic findings were variable, being diffuse mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, focal glomerulonephritis and focal glomerulosclerosis respectively in each case.

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