All issues > Volume 21(12); 1978

Original Article

J Korean Pediatr Soc. 1978;21(12):1103-1109. Published online December 31, 1978.

The Relationship between Creatinine Clearance and Height in Korean Children.

Sung Hee Oh

¹Department of Pediatrics, College of Medicine, Seoul National University, Korea.

Abstract

The estimation of glomeruIar filtration rate is of central importance in assessment of renal function. Especial1y, simple and rayid method to estimate glomerular filtration rate is necessary in chiIdren. Examples of its application include the adjustment of dosage of drugs such as digoxin, kanamycin, gentamycin, which are mainly excreted by the kidney, and monitoring of gross change in renal function after initial assessment by a more precise although more complicated method. This study was directed to find out the relationship between creatinine clearance and height/serum creatinine. 27 healthy korean children were Sampled among house-dwelling children and hospitalized convalescent children, who had no renal disease and were in no muscular wasting status. The concentration of creatinine has been measured by autoanalyzer. Based on statistical analysis of data, a formula 'was derived which allows estimation of glomerular filtration rate from plasma creatinine concentration and height. The equation obtained was as follows: Ccr(ml/min/1.73m2) =0. 40 0 x Ht(cm)/Pcr (mg %) +18. 7 (r: 0.621)

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