All issues > Volume 21(9); 1978

Original Article

J Korean Pediatr Soc. 1978;21(9):573-581. Published online September 30, 1978.

Hemolytic Uremie Syndrome.

K C Kim¹, H K Lee¹, K Y Kim¹, D J Yun¹, K J Cho²

¹Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
²Department of Orthopedic surgery, Physical medicine and Rehabilitation Yonsei University College of Medicine, Seoul, Korea.

Abstract

Hemolytic uremic syndrome is a relatively ne fatal disease in infants We have been found 6 cases of hemolytic uremic syndrome at pediatric department of Yonsei Medical Center from Septemer, 1970 to August, 1976. Clinical study was taken with our literrature review. The results are follow: 1. Prodromal symptoms are vomiting, URI symptoms, abdominal pain and etc. 2. Clincal symptoms are mostly edema, dehydration, fever, oliguria, irritability, pallor, hepatomegaly and lethargy. 3. Acute renal failure was more severs in infants rather than in older children. Duration of oliguria was 8.75 days in infants and 4.5 days in older children. 4. Platelte count was decreassed in all cases. After heparin therapy, platelet count was increased to normal level in 3 cases 5. Prothrombin time became to be normal level during heparin therapy in 3 cases 6. Blood urea nitrogen was high in 4 cases and it was contiuously increased. Among them, 3 cases was expired. 7. Heperinization was effective in 3 cases, steroid was not effective. And peritoneal dialysis and exchang transfusion were performed in each 1 case.

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