All issues > Volume 20(12); 1977

Original Article

J Korean Pediatr Soc. 1977;20(12):959-964. Published online December 31, 1977.

Comparison of Tuberculine Testing Between Monotest and Mantoux.

Byong Kwan Son¹

¹Department of Pediatrics, College of Medicine, Seoul National University, Korea.

Abstract

The Monotest was compared with the Mantoux test. A total of 527 first grade primary school children were subjected to test. Each child was innoculated simultaneously to one side arm with protein purified derivatve(PPD, 1TU) and to the another side arm with Monovac(Institute Merieux). Results from each test were read seperately 72 hours after administration. When induration of 2mm or greater was considered a positive Monotest reaction and compared to a positive Mantoux reaction of 10mm or greater, the sensitivity of Monotest to mantoux test was 96.19% and the specificity was 88.39%. When induration of 5mm or greater was considered a positive Monotest reaction and compared to a positive Mantoux reaction of 10mm or greater, the sensitivity of Monotesto to to Mantoux test was 81.90% and the specificity was 96.68%. From this results I would assume that the Monovac test can be substituted for Mantoux test(PPd, 1TU), preferably 2mm or greater swelling of Monovacc test is considered as a positive result.

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