All issues > Volume 20(4); 1977

Original Article

J Korean Pediatr Soc. 1977;20(4):271-278. Published online April 30, 1977.

Clinical Studies on Purpura.

Kir Young Kim¹, Ki Sup Chung¹, Hong Kyu Lee¹, Hun Young Moon¹, Ki Young Lee¹, Duk Jin Yun¹

¹Department of Pediatrics, College of Medicine, Yonsei University, Korea.

Abstract

We observed clinically 150 cases who were admitted with complaing of purpura at the Pediatric Department of Severance Hospital Yonsei University College of Medicine during a period of 9 years from July, 1966 to June, 1975. In 150 cases, leukemia, 33 cases (22.0%), was most common disease, followed by I.T.P., allergic purpura, meningococcemia, aplastic a nemia, sepsis in order aqnd the incidence was 20.0% (30 cases), 19.3% (29 cases), 19.3% (29 cases), 14.0% (21 cases), 4.0% (6 cases) respectively. And we observed 1 case of thrombocytopenic purpura complicated with scarlet fever and primary hypersplenism respectively. The highest incidence was between the age of one and six years, and males were affected more frequently than females. Clinical manifestations were anemia, fever, abdominal pain, vomiting, joint pain in general symptoms and nasal bleeding, melena, gum bleeding in hemorrhagic symptoms. Major symptoms were fever, abdominal pain, anemia, na sal bleeding, melena, gum bleeding in thrombocytopenic purpura, and fever, abdominal pain, vomiting, meningeal irritation signs in non-thrombocytopenic purpura. I the laboratory findings, mean value of platelet count was below 40,000/mm(3) in thrombocytopenic purpura, but 190,000/mm(3) in non-thrombocytopenic purpura. And bleeding time was prolonged above 5 minutes in thrombocytopenic purpura, but was below 1 minute in non-thrombocytopenic purpura.

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