All issues > Volume 34(12); 1991

Original Article

J Korean Pediatr Soc. 1991;34(12):1740-1744. Published online December 31, 1991.

A case of transient myeloproliferative disorder in Down's syndrome.

Dong Uk Kim¹, Woo Ki Lee¹, Eung Won Park¹, Kwang Woo Kim¹

¹Department of Pediatrics, Sunrin Hospital, Pohang, Korea

Received: May 9, 1991;  Accepted: July 25, 1991.

Abstract

Transient myeloproliferative disorder has been reported in infants with Down’s syndrome. This disorder is clinically and hematologically indistinguishable from congenital leukemia. In contrast to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months of diagnosis without antileukemic treatment. We experienced a case of Transient myeloproliferative disorder with Down’s syndrome. This 4-day-old female neonate showed jaundice, hepatomegaly, fever, dyspnea, mongoloid face and congenital heart disease (VSD). A brief review of literatrue was made

Keywords :Down's syndrome;transient myeloproliferative disorder