All issues > Volume 34(12); 1991

Original Article

J Korean Pediatr Soc. 1991;34(12):1730-1735. Published online December 31, 1991.

A case of acute megakaryoblastic leukemia with Down syndrome.

Sung Jin Chang¹, Sung Min Sohn¹, Heung Sik Kim¹, Chin Moo Kang¹, Dong Seok Jeon²

¹Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea
²Department of clinical pathology, Keimyung University, School of Medicine, Taegu, Korea

Received: May 23, 1991;  Accepted: July 26, 1991.

Abstract

We experienced a case of acute megakaryoblastic leukemia (M7) with Down syndrome. The patient was admitted due to premature SGA, which revealed characteristic facial figure of Down syndrome. M7 was diagnosed with PB smear which showed abundant megakaryoblast and confirmed by using the monoclonal antiplatelet glycoprotein IIb/IIIa antibody (J 15). On 25th hospital day, the patient gained weight but discharged without further treatment of M7. Authors report the case with review of literature.

Keywords :Acute megakaryoblastic leukemia (M7) Down syndrome