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All issues > Volume 2(2); 1959

Case Report
J Korean Pediatr Soc. 1959;2(2):131-135. Published online September 30, 1959.
DIABETES MELUTUS IN INFANT
Dong-Shik Chin1, Eui-Sun Lim1
1Department of Pediatrics, Yonsei University College of Medicine
Abstract
Diabetes mellitus in infant under 1 year of age is rare. White, in studing 750 patients with juvenile diabetes, found that in only 0.5 per cent had the onset before the age of one. Joslin, in a study of 1,430 diabetic children, found a similar incidence(0.5 per cent). In Korea, we were not aWe to find any previous report of juvenile diabetes under 15 years of age. Because of the rarity, we are presenting this report of a patient oa our service- Case report A 6 months old Korean male infant was admitted to Severance Hospital on December 12, 1958, with stickiness of urine, dysuria(crying on urination) and failure to gain weight for his age. His grand-grand mother, who had every evidence of diabetes mellitus but this was not confirmed medically, had died of cancer. Otherwise family history was not contributory. On admission, the patient weighed 6.25kg and appeared moderately dehaydrated Fasting blood sugar was 467mgm per 100 ml. of blood. A urinalysis showed a 4 plus sugar and 3 plus acetone. The patient was put on regular insulin one unit daily at first and insulin dosage was gradually increased intending to control blood sugar between 100 to 200 mgm% while patient was on breast and additional bottles as before his admission. On December 13, 1958, regular insulin was raised to 3 units at 4 houns intervals (15 units a day). Above method was continued until January 13, 1959, at this time blood sugar was controlled between 51 to 263 mgm. On January 14, 1959, isophane(N.P. H.) insulin 10 units was given in order to avoid repeated injection of regular insulin. At this time his blood sugar was ranged between 82 to 201 mgm% (table 2.) The hospital course was satisfactory. Patient had gained his body weight considerably, and recovered good turgor of the skin. The delay in management can be attributed to that of cautiousness for the determining an accurate insulin dosage without risk of developing hypoglycemia and also that his blood sugarlevel was so easily fluctuating. Up to the present, isophane insulin 10 units a day is successfully administered in controlling his diabetes.

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