Clinical and Experimental Pediatrics

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All issues > Volume 3(2); 1960

Original Article
J Korean Pediatr Soc. 1960;3(2):41-47. Published online October 31, 1960.
ON THE CYTOPLASMIC INCLUSIONS SEEN IN HUMAN THROAT EPITHELIAL CELLS
Byung Ho Choi1, Chan Ock Park2
1Yonsei University Medical School, Seoul, Korea
2Department of pediatrics, Akron Children's Hospital, Akron, Ohio, U.S.A.
Abstract
Cytoplasmic inclusions have been identified in throat epithelial cells of 82 cases out of 92 cases studied. The inclusions occur in a high percentage when there is some degree of throat irritation. They are found more abundantly and frequently in patients with chronic throat irritations and in measles than in normal persons. Various special stains utilized tend to favor these structures being composed of ribosenucleic acid and not representing artefacts or normal components of cells. Their morphology has been described and the resemblance to certain viral inclusions has been pointed out. Although there is a possibility of these bodies being of viral nature, there have been no positive proofs for this speculation in the present study.

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