All issues > Volume 14(3); 1971

Original Article

J Korean Pediatr Soc. 1971;14(3):163-170. Published online March 31, 1971.

Clinical Studies of Leukemia in Childhood

Jwa Sin Kim¹, Young Ho Lieu¹, Keun Chan Sohn¹, Keun Soo Lee¹

¹Dept, of Pediatrics, The National Medical Center, Seoul, Korea.

Abstract

A total of 74 cases of leukemia in children who were admitted at The National Medical Center from January 1960 to July 1969 were anaysed clinically and hematologically. 1.The incidence of leukemia was about 4 per 1, 000 patients who admitted during the same period. 2.Male patients were more prevalent being male to female ratio 2. 7:1. 3.The 6~7 year old age group showed the highest morbidity (21. 6%) with 52.1% in up to 7 years old age. 4.The incidence of the various cytological types was as follows: Acute lymphocytic 40. 5%, acute myelocytic 28.2%, undifferentiated leukemia 16%, chronic myelocytic 9%, acute monocytic 5% and erythroleukemia 1. 3%. 5.Common chief complaints were pallor (85.1%), fever(71. 6%), general weakness(55. 5%), bleeding tendency (52. 7%), headache (33. 8%), abdominal pain and others. 6.Common objective signs were hepatomegaly (64. 7%), lymphnode swelling (60. 8%), purpura (48. 6%), splenomegaly(46%), edema (20.2%) and others. 7.Hemoglobin value below 4G% was found in 10 cases (13. 5%), below 6 G% in 36 cases(48. 6%) and above 10G% in 6 cases(8.1%). 8.Leucoyxte count were variable: 5,000-100,000/mm3 in 15 cases (20. 3%), marked leucocytosis (above 50, 000/mm3) in 17 cases (22. 9%) and leucopenia in 17 cases (22. 9%). 9.Platelets were decreased in number and it related closely to bleeding tendency. Marked throm-bocytopenia; in 32 cases (45. 7%). 50,000-150,000/mm3 in 25 cases (35.1%} and 200,000/mm3 in 5 cases (7.2%).

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