All issues > Volume 10(5); 1967

Case Report

J Korean Pediatr Soc. 1967;10(5):281-288. Published online May 31, 1967.

A Case Report of Morquio’s Disease

J.J. Cho¹, S.T. Kim¹, D.K. Kim¹, D.S. Kim¹, I.S. No²

¹Depart, of Pediatrics,College of Medicine,Pusan National University
²The Save The Children Fund Clinic in Pusan Korea

Abstract

A case of Morquio’s disease in a child aged eighteen months is reported. He showed normal intelligence, but stunted growth with short trunk and proportionately long limbs, pectus carinatum and kyposcoliosis. There were slight muscular weakness and the left inguinal hernia. There was radiological evidence of the disturbance of osteogenesis in epiphyses and diaphyses, especially vertebra plana, central tongue, flaring of metaphyses, shallowing and widening of the acetabular cavity, irregular and delayed appearance of ossification centers, osteoporosis and kyposcoliosis, all common findings in Morquio’s disease. However, he did not show any of the followings； hepatosplenomegaly, corneal opacity or Reilly bodies in peripheral blood and bone marrow. There were no specific biochemical :changes, but serum phosphorus and radioactive iodine (I131) uptake were slightly increased and serum calcium was decreased. There was no history of consanguinity, and no other members of the family were afflicted with this disease. A brief review of relevant literatures is also included.

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