All issues > Volume 18(1); 1975

Original Article

J Korean Pediatr Soc. 1975;18(1):22-28. Published online January 31, 1975.

Comparative Observations Between Serum Glutamic Oxaloacetic Transaminase and Glntamic Pyruvic Transaminase in Acute Viral Hepatitis

Ghun Shik Ihm¹

¹Department of Pediatrics, Yonsei University College of Medicine Seoul,Korea

Abstract

Transaminase is the enzyme that catalyze the reversible transfer of an alpha amino group from an amino acid to an alpha keto acid. This enzyme was first discovered by Braunstein and Kritzman in 1937 in pigeon breast muscle. Although a large number of substrate specific transaminases have been described in the serum _glutamic oxaloacetic transaminase (SGOT) and glutamic pyruvic transaminase (SGPT). Since the valuable significance of determination of serum trnsaminase levels as so called liver function test in clinical fields was introduced, many review articles have been published in the past years. The author clinically compared of SGOT and SGPT in 140 patients with acute viral hepatitis who were admitted to the department of pediatrics and of internal medicine at Severance Hospital and confirmed the fact that in acute viral hepatitis the measurement of SGPT alterations has been found to a useful tool in the diagnosis and study and appears to be more sensitive than SGOT.

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