All issues > Volume 18(5); 1975

Original Article

J Korean Pediatr Soc. 1975;18(5):391-400. Published online May 31, 1975.

Vitamin D Deficiency Rickets

Soo Jee Moon¹, Young Won Kim¹, Chong Moo Park¹

¹Department of Pediatrics, Hanyang University College of Medicine Seoul, Korea

Abstract

Vitamin D deficiency rickets are still important problem in many countries especially developing snd underdeveloped countries. We experienced 8 cases o£ Vitamin D deficiency rickets from May, 1973 to Aug. 1974. All 8 cases had. no history of any Vitamin suppl ementation. Serum calcium, phosphorus and alkaline phosphatase levels were revealed rachitic changes. Confirmatory diagnosis was made by X-ray examination. We divided patient into oral and parenteral therapy group. 1. One of eight cases was given 20, 000 IU/day IM injection of Vitamin D for 30 days. 2.One of eight cases was given 200,000 IU every other day IM injection of Vitamin D 3 times, 3. Two of eight cases were given a large single dose 600,000 IU. IM injection of Vitamin D 4.Two of eight cases were given 5, 000 IU/day per os for 4months. 5.Two of eight cases were given 20,000 IU/day for 1 months. 600,000 IU of total amount of Vitamin D for two groups was given, when we had found no toxic symptoms and signs with Vitamin D such as hypercalcemia, hypercalciuria, anorexia, irritability, lethargy and muscular hypotonia in all patients. There were no significant difference in the course and result of treatment. All cases had good Jhealing process and improvement clinically, biochemically and roentgenogram. Literature review was made briefly.

Keywords :