All issues > Volume 17(6); 1974

Case Report

J Korean Pediatr Soc. 1974;17(6):449-454. Published online June 30, 1974.

Systemic Cryptococcosis

S.K. Kim¹, K.J Nam¹, S.H Shin¹, K.J Kim¹, D.K Chung²

¹Department of Pediatrics Presbyterian Medical Center’ Jeon-ju, Cheon-buk, Korea
²Department of Clinical Pathology Presbyterian Medical Center’ Jeon-ju, Cheon-buk, Korea

Abstract

Cryptococcal infection is now not so rare a disease in Far East Asia. The7 authors present two esses of systemic cryptococcosis experienced in our pediatric department. Casel had involvement of the liver, spleen, kidney, lymph nodes, adrenal glands and brain, and case 11 C.N.S. and liver. Numerous cryptococcus neofor mans were found in the affected organs and tissues. The authors discuss incidence, diagnostic problems and drugs. Routine India ink preperation and repeat of spinal fluid examination were emphasized in the case sof meningitis. In ambiguous cases, urine, sputum, blcod, bone marrow and stool examination can help identify a fungus infection. Amphotericin-B is the most effective drug to combat fungal infection up to present. 5-fluorocy-tocine is a new drug, but more evaluation is required because of little experience with it.

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