All issues > Volume 15(4); 1972

Original Article

J Korean Pediatr Soc. 1972;15(4):319-325. Published online April 30, 1972.

Leukemia in Childhood with Mediastinal Masses

Min Ja Pai¹, Soon Young Kim¹, Don Hee Ahn¹, Chang Yee Hong¹

¹Department of Pediatrics, College of Medicine, Seoul National University

Abstract

Six cases o£ acute leukemia with mediastinal masses are reported with a review of relevant literature.. Out of 105 patients wi h leukemia who had been admitted to the Department of Pediatrics, Seoul. National University Hospital for the last 6 years, six cases had huge mediastinal masses on the chest x-ray examination. In 3 of them the masses were located in the anterior mediastinum, suggesting enlargement of the thymus. On admission these cases had more or less severe dyspnea and facial edema,, and 2 of them were initally suspected as heart failure and osteomyelitis respectively. All of the 6. cases were acute lymphocytic leukemia and treated with combinations of prednisolone, 6-mercaptcpurine^
metho
trexate and vincristine, showing remarkable improvement of clinical features in a few days.

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