All issues > Volume 12(4); 1969

Original Article

J Korean Pediatr Soc. 1969;12(4):175-180. Published online April 30, 1969.

Clinical Reactions and Effect on the Platelet Count in the Peripheral Blood After Live Attenuated Measles Virus (Lirugen) Vaccination

Jae Choon Lee¹, Byung II Kim¹, Doo Hong Ahn¹, Dong Sup Han¹

¹Derartment of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea

Abstract

Live attenuated measles virus (Lirugen) was vaccinated in 14 susceptible children. The mean maximum rectal temperature was 100.2 °F, and anorexia, cough, ri nor rhea were observed in some vaccinated children, but the rashes were not developed in all cases. Total WBC count was mildly decreased 1 week after vaccination which were within normal limits. Differential count showed that lymphocytes were increased 9 days after vaccination, segments were conversely decreased. All vaccinated children showed a fall in platelet counts with a mean maximum fall of 69,000 and it was noted 12 days after vaccination. Warthin-Finkeldey giant cell on the nasal or buccal mucous membrane was not present in all vaccinated children.

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