All issues > Volume 12(4); 1969

Original Article

J Korean Pediatr Soc. 1969;12(4):181-186. Published online April 30, 1969.

Clinico-immunologic Reaction and Effect on the Platelet Count following Measles Vaccination of Schwarz Strain

J.S. Kim¹, S.C. Chang¹, K.H. Kim²

¹Dept, of Pediatrics, Seoul Red Cross Hospital
²National Institute of Health

Abstract

Clinical and immunologic reactions were observed on 152 orphan children who were injected Schwarz Strain of measles vaccine. And also, platelet was counted to observe the effect o£ measles vaccine on the platelet. In these procedures, we could obtain the following results: 1) Febrile reactions were observed in 34.2% of total 152 children whom measles vaccine were injected. 2)Mean duration of fever was 1. 8 days, and mean time of appearence of febrile reactions was 9.1th day after vaccination. 3)Immunologic reactions were positive in 9 out of 11 children examined. The mean neutralization titer was 1 : 55.6. 4)Platelet was decreased in 43. 2% of vaccinated children. Effect on the platelet of Schwarz Strain was less marked than that of Edmonston strain.

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