All issues > Volume 15(6); 1972

Original Article

J Korean Pediatr Soc. 1972;15(6):477-492. Published online June 30, 1972.

Experimental Study on Insulin acting Areas of the Central Nervous System in BSP Excretion

Yung Kil Chang¹

¹Department of Pediatrics, College of Medicine, Seoul National University Seoul, Korea

Abstract

The object of this study is to investigate the effects of various areas of the central nervous system on BSP excretion of the liver. The Korean male rabbits weighing 1. 8 kg were subjected for study, and 0. 5u of insulin was injected into both regions of the central nervous system symmetrically. The following are observed; 1. There was neither increased in bile nor BSP excretion when such areas as putamen, globus pallidus, anterior hypothalamus, posterior hypothalamis, midmedial hypothalamus, hippocampus, preoptic area, midbrain and nucleus salivarius were injected with insulin respectively. 2. There were markedly increased in both bile and BSP excretion when the three areas; caudate nucleus, midlateral hypothalamus, and mammillahy body were injected with insulin respectively. The above mentioned experimental findings lead this author to conclude the regulating centers which cause to increase in BSP excretion exist in caudate nucleus, midlateral hypothalamus and mammillary bony.

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