All issues > Volume 15(12); 1972

J Korean Pediatr Soc. 1972;15(12):1104-1111. Published online December 31, 1972.

The Clinical Study for The Rebound Phenomenon After The Exchange Transfusion In Neonate

KookChoo Rie¹, SangWoo Kim¹, SoonYoung Kim¹, ChongKoo Yun¹

¹Department of Pediatrics, college of medicine, Seoul, National University,Korea.

Abstract

57 newborn infants who were underwent exchange transfusion in Seoul National University Hospital from Jan. 1970 to Sept. 1972 were analysed. (1) 44% of the cases(25 cases among 57 cases) needed repeated exchange transfusions. (2) There was a tendency of requring the:repeated exchange transfusion when the first exchange transfusion was underwent in an earlier age. ⑶ There seemed to be no relationship between the birth weight and the frequency of exchange transfusion. (4) 48% of the isoimmunized patients (14 cases among 29 cases) and 24% of non-isoimmunized patients (6 cases among 25 cases) needed the repeated exchange transfusion. (5) 4 types of bilirubin rebound were noticed after the exchange transfusion. a. In 24 of 57 cases, the bilirubin rebound was so mild that only one exchange transfusion was sufficient to treat the neonatal hyperbilirubinemia. b. In 2 of 57 cases, the bilirubin rebound was almost absent. c. In 13 of 57 cases, the bilirubin rebound was so high, almost equal to or above the pre-exchange level, that the repeated exchange transfusion was needed. d. In 11 o£ 57 cases, the bilirubin rebound was high above the level of 20 mg% but under the pre- exchange level. The repeated exchange transfusion was also needed. (6) The serum bilirubin level was decreased to 46. 5% of the pre-exchange level immediate after the exchange transfusion.

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