All issues > Volume 11(4); 1968

Original Article

J Korean Pediatr Soc. 1968;11(4):189-192. Published online April 30, 1968.

Hydrocortisone Levels in Cerebrospinal Fluid and Urine of Encephalitis Patients

Young Tai Chang¹

¹Department of Pediatrics, and Department of Biochemistry Chonnam University Medical School, Kwangju

Abstract

1.Hydrocortisone levels in cerebrospinal fluid and urine have been determined in normal children and in encephalitis patients before and after the administration of hydrocortisone or prednisolone. 2.A significant but trace amount of hydrocortisone was detected in normal cerebrospinal fluid. Encephalitis caused a threefold increase in the hydrocortisone level of cerebrospinal fluid, which was further increased by hydrocortisone administration. 3.Urinary excretion of hydrocortisone was not influenced by encephalitis, but increased when either hydrocortisone or prednisolone was administered.

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