Clinical and Experimental Pediatrics

Search

Search

Close


Warning: fopen(/home/virtual/pediatrics/journal/upload/ip_log/ip_log_2025-04.txt) [function.fopen]: failed to open stream: Permission denied in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 93

Warning: fwrite(): supplied argument is not a valid stream resource in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 94

All issues > Volume 68(4); 2025

Lee: Advancements and challenges in neonatal resuscitation: embracing laryngeal mask airways for improved outcomes

Advancements and challenges in neonatal resuscitation: embracing laryngeal mask airways for improved outcomes

Jang Hoon Lee, MD, PhD
Corresponding author: Jang Hoon Lee, MD, PhD. Department of Pediatrics, Ajou University School of Medicine, 164, Worldcup-ro, Yeongtong-gu, Suwon 16499, Korea Email: neopedlee@ajou.ac.kr
Received July 22, 2024       Revised September 19, 2024       Accepted September 19, 2024
Key message
Despite advancements in perinatal medicine, the prevention of hypoxic-ischemic encephalopathy through appropriate neonatal resuscitation remains a major issue in neonatology. While 90% of all neonates successfully transition from fetal to neonatal life without requiring special assistance during the birth process, 10% require some level of resuscitative intervention and 1% require extensive neonatal resuscitation [1].
Neonatal resuscitation is an essential clinical competency for medical professionals in the field of perinatal medicine. Unlikely adult cardiac life support, which is primarily required due to cardiac issues, neonatal resuscitation is typically required due to ventilation issues. Therefore, positive pressure ventilation (PPV) is the most critical intervention provided during delivery room resuscitation, and its application frequency varies according to the neonate’s gestational age and other factors. In previous studies, 3.6%–8.1% [2-5] of all in- or liveborn infants required PPV at birth; of them, younger preterm infants had greater need [6]. Fig. 1 shows a flow chart of the newly updated neonatal resuscitation algorithm [7].
Yamada et al. [8] analyzed errors occurring during neonatal resuscitation through video recordings and found that the second most common error of commission (at 43.5%) was performing PPV with insufficient peak inspiratory pressure or providing inappropriate peak inspiratory or positive end-expiratory pressure.
The 7th edition of the American Neonatal Resuscitation Program guidelines [9] recommended the use of a laryngeal mask airway (LMA) as an alternative to an endotracheal tube in neonates weighing more than 2 kg. In the new guidelines [10], this recommendation has been expanded to suggest the use of LMA versus face masks for PPV. In this context, Song and Jeon [11] reviewed its routine for PPV. Neonatal resuscitation education provided by medical institutions and professional societies must include evidence-based information and hands-on training related to this practice. Such education will help more healthcare providers become familiar with and appropriately use LMA during delivery room resuscitations. Furthermore, additional clinical research is needed to provide evidence of the efficacy of LMA in smaller and more premature infants.
Footnotes

Conflicts of interest

No potential conflict of interest relevant to this article was reported.

Funding

This study received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Fig. 1.
Neonatal resuscitation algorithm. CPAP, continuous positive airway pressure; ECG, electrocardiography; ETT, endotracheal tube; HR, heart rate; IV, intravenous; O2, oxygen; SpO2, oxygen saturation; UVC, umbilical venous catheter. Reproduced with from Aziz K, et al. Circulation 2020;142(16_suppl_2):S524-50,7) with permission of American Heart Association, Inc., and American Academy of Pediatrics.
cep-2024-01088f1.tif
References

1. Kattwinkel J, Denson S, Zaichkin J, American Heart Association; American Academy of Pediatrics Committee on Fetus and Newborn; American Academy of Pediatrics; et al. Textbook of neonatal resuscitation. 4th ed. Itasca (IL): Amer Academy of Pediatrics, 2000.
2. Niles DE, Cines C, Insley E, Foglia EE, Elci OU, Skåre C, et al. Incidence and characteristics of positive pressure ventilation delivered to newborns in a US tertiary academic hospital. Resuscitation 2017;115:102–9.
[Article] [PubMed]
3. Bjorland PA, Øymar K, Ersdal HL, Rettedal SI. Incidence of newborn resuscitative interventions at birth and short-term outcomes: a regional population-based study. BMJ Paediatr Open 2019;3:e000592.
[Article] [PubMed] [PMC]
4. Skåre C, Kramer-Johansen J, Steen T, Ødegaard S, Niles DE, Nakstad B, et al. Incidence of newborn stabilization and resuscitation measures and guideline compliance during the first minutes of life in Norway. Neonatology 2015;108:100–7.
[Article] [PubMed]
5. Ersdal HL, Mduma E, Svensen E, Perlman JM. Early initiation of basic resuscitation interventions including face mask ventilation may reduce birth asphyxia related mortality in low-income countries: a prospective descriptive observational study. Resuscitation 2012;83:869–73.
[Article] [PubMed]
6. Yoon SJ, Lim J, Han JH, Shin JE, Eun HS, Park MS, et al. Impact of neonatal resuscitation changes on outcomes of very-low-birth-weight infants. Sci Rep 2021;11:9003.
[Article] [PubMed] [PMC]
7. Aziz K, Lee HC, Escobedo MB, Hoover AV, Kamath-Rayne BD, Kapadia VS, et al. Part 5: neonatal resuscitation: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 2020;142(16_suppl_2): S524–50.
[Article] [PubMed]
8. Yamada NK, Yaeger KA, Halamek LP. Analysis and classification of errors made by teams during neonatal resuscitation. Resuscitation 2015;96:109–13.
[Article] [PubMed]
9. American Academy of Pediatrics; American Heart Association. Alternative airways: endotracheal tubes and laryngeal masks. Weiner GM, Zaichkin J, editors. Textbook of neonatal resuscitation. 7th ed. Itasca (IL): American Academy of Pediatrics, 2016;:115–61.
10. American Academy of Pediatrics; American Heart Association. Positive-pressure ventilation. Weiner GM, Zaichkin J, editors. Textbook of neonatal resuscitation. 8th ed. Itasca (IL): American Academy of Pediatrics, 2021;:65–116.
11. Song ES, Jeon GW. Updates in neonatal resuscitation: routine use of laryngeal masks as an alternative to face masks. Clin Exp Pediatr 2024;67:240–6.
[Article] [PubMed] [PMC]

Go to Top