| The Incidence of Hypothyroidism in Children with Down Syndrome |
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Seong Hyeon Jeon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim |
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Department of Pediatrics, Kwangju Christian Hospital, Kwangju, Korea |
| Down증후군 환아에서 갑상선기능저하증의 빈도 |
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전성현, 조춘호, 김경심, 김기복 |
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광주 기독병원 소아과 |
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| Abstract |
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A review of Thyroid function tests was performed on 32 children with Down syndrome confirmed by cytogenetic examination at the Dept. of Pediatrics, Kwangju Christian Hospital from Jan.1989 to Feb.1990.
1) Twenty among 32 children with Down syndrome were male, with the sex ratio being 1.7 : 1. Their ages ranged from 3 days to 5 years, with the mean age of 14.2 months, the majority(5 3.1%) being between 1 month to 1 year. The most frequent Karyotype found in Down syndrome was 21-trisomy(97%), followed by Translocation(3%).
2) The two cases of hypothyroidism(6.3%) and four cases of compensated hypothyroidism (12.5%) were revealed. Thyroid autoantibodies were detected in 2 cases(6.3%) with Down syndrome. |
| Key Words:
Down syndrome, Hypothyroidism |
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