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Original Article
Role of neutrophil elastase in predicting infection among children with chemotherapy-induced febrile neutropenia
Mahmoud A. El-Hawy, Doaa M. Elian, Mai El-Sayad Abd El-Hamid, Esraa T. Allam, Mariam S. Kandeel, Asmaa A. Mahmoud
Background: Infection is a significant cause of death following chemotherapy-induced febrile neutropenia (FN). Neutropenia and compromised neutrophil function are the primary reasons for the decreased defense against infections.
Purpose: This study aimed to evaluate the significance of neutrophil elastase (NE) in predicting the outcomes of childhood hematological malignancies with FN. Methods: The study included 64 patients with FN and 64 healthy children...
DOI: https://doi.org/10.3345/cep.2025.00318    [Epub ahead of print]
Clinical course of children with postinfectious bronchiolitis obliterans with versus without comorbid bronchopulmonary dysplasia
Lamia Medghoul, Julien Grosjean, Christophe Marguet, Hortense Petat
Background: Postinfectious bronchiolitis obliterans (PIBO) is a rare chronic obstructive pulmonary disease that occurs after a respiratory infection. Its diagnosis is generally based on clinical history, respiratory symptoms, and computed tomography (CT) findings.
Purpose: Here we evaluated the frequency of exacerbations, clinical progress, and inhaled corticosteroid (ICS) usage in children diagnosed with PIBO with or without comorbid bronchopulmonary dysplasia (BPD). Methods: This...
DOI: https://doi.org/10.3345/cep.2025.00122    [Epub ahead of print]


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