Ahead-of Print
- Page Path
-
- HOME
- BROWSE ARTICLES
- Ahead-of Print
Articles in E-pub version are posted online ahead of regular printed publication.
- Editorial
- Beyond the eye: a multidisciplinary perspective on managing pediatric myopia
-
Eoi Jong Seo
-
-
|
|
Myopia is a growing global public health concern because of its association with irreversible vision loss such as myopic traction maculopathy, rhegmatogenous retinal detachment, and glaucoma. The effective prevention of myopia in childhood requires a multidisciplinary approach that integrates ophthalmologic care with lifestyle, nutrition, and sleep interventions. Early detection through regular visual screening in schools and primary care settings and timely ophthalmology referrals are critical to preventing high myopia. |
-
-
- Treatment targeting pediatric inflammatory bowel disease-associated anemia: experience from a single tertiary center
-
Ana S.C. Fernandes, Sara Azevedo, Ana Rita Martins, Ana Isabel Lopes
-
-
|
|
Question: Does treating iron deficiency (ID) using intravenous iron in pediatric inflammatory bowel disease (IBD) feature long-term safety and efficacy?
Finding: Intravenous iron supplementation was safe and effective. However, the ID recurrence rate was higher than expected.
Meaning: Proactive screening and treatment of ID in pediatric IBD are essential. The Ganzoni formula likely underestimates the iron requirements of pediatric patients. Prospective trials are needed to optimize iron treatment dosing. |
-
-
- Role of neutrophil elastase in predicting infection among children with chemotherapy-induced febrile neutropenia
-
Mahmoud A. El-Hawy, Doaa M. Elian, Mai El-Sayad Abd El-Hamid, Esraa T. Allam, Mariam S. Kandeel, Asmaa A. Mahmoud
-
-
|
|
Background: Infection is a significant cause of death following chemotherapy-induced febrile neutropenia (FN). Neutropenia and compromised neutrophil function are the primary reasons for the decreased defense against infections.
Purpose: This study aimed to evaluate the significance of neutrophil elastase (NE) in predicting the outcomes of childhood hematological malignancies with FN.
Methods: The study included 64 patients with FN and 64 healthy children... |
-
-
- Clinical Note
- Expanding genotype-phenotype correlation of Kenny-Caffey syndrome type 1
-
Manuela Lo Bianco, Federica Sipala, Xena Giada Pappalardo, Gaia Fusto, Roberta Rizzo, Federico Favata, Carla Cimino, Silvia Marino, Martino Ruggieri, Agnese Suppiej, Simone Ronsisvalle, Raffaele Falsaperla
-
-
-
-
- Review Article
- Myopia: a review of current concepts, association with nonophthalmological conditions, and treatment strategy in children and adolescents
-
Yeon Woong Chung
-
-
|
|
Myopia is a major ophthalmological disorder with increasing prevalence worldwide, particularly in East Asia. Evidence indicates that its development involves complex interactions between genetic and environmental factors. Body stature, sleep patterns, and nutritional status significantly influence the progression of myopia during childhood and adolescence. Its treatment and prevention strategies include optical correction, atropine therapy, increased outdoor activity, decreased near work, and regular retinal monitoring. |
-
-
- Original Article
- Establishing an induced pluripotent stem cell bank using urine cells from pediatric patients with neurogenetic diseases
-
Hien Bao Dieu Thai, WonWoo Jung, Sol Choi, Woo Joong Kim, JangSup Moon, ByungChan Lim
-
-
|
|
Question: What can be used to create a reliable supply of somatic cells for induced pluripotent stem cells (iPSCs) generation and standardize procedures for building an iPSC bank for researching pediatric neurogenetic disorders?
Findings: Noninvasively acquired urine cells are a desirable cell source for iPSC reprogramming.
Meaning: An iPSC bank can be created from diverse patient cell sources and offer a useful resource for translating research results into clinical therapy for pediatric neurogenetic disorders. |
-
-
- Hematopoietic stem cell transplantation in pediatric patients with type VI mucopolysaccharidosis
-
Vedat Uygun, Koray Yalçın, Hayriye Daloğlu, Seda Öztürkmen, Suna Çelen, Suleimen Zhumatayev, Gülsün Karasu, Akif Yeşilipek
-
-
|
|
Question: Could hematopoietic stem cell transplantation (HSCT) be an alternative to enzyme replacement therapy (ERT) for type VI mucopolysaccharidosis (MPS VI)?
Finding: HSCT is generally not offered due to reports of high toxicity and mortality. However, we detected fewer complications and graft-versus-host disease cases and no deaths with HSCT.
Meaning: HSCT is both less expensive than ERT and permanent; thus, it should be considered an alternative treatment for MPS VI. |
-
-
- Somatic symptom severity during acute illnesses among children with functional gastrointestinal disorders
-
Rattanachart Sirinil, Anundorn Wongteerasut
-
-
|
|
Functional gastrointestinal disorders (FGIDs) are associated with various somatic symptoms measured using a visual analogue scale and the Children’s Somatic Symptoms Inventory-24 questionnaire. Children with FGIDs exhibited more significant somatic symptoms than controls during acute illnesses. Gastrointestinal (GI) and non-GI manifestations are significantly more common in children with FGIDs. |
-
-
- Serum amyloid A and proadrenomedullin as early markers in critically ill children with sepsis
-
Nagwan Y. Saleh, Wafaa M. Abo El Fotoh, Mona S. Habib, Salem E. Deraz
-
-
|
|
Question: Are serum amyloid A (SAA) and proadrenomedullin (proADM) levels early markers in critically ill children with sepsis?
Finding: This prospective case-control study included 65 critically ill children with sepsis admitted to the pediatric intensive care unit and 31 controls. SAA and proADM levels were significantly higher in patients versus controls.
Meaning: SAA and proADM are promising biomarkers for diagnosing and predicting outcomes in pediatric sepsis. |
-
-
