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Exercise Induced Delayed Bronchoconstriction in children with Asthma

Journal of the Korean Pediatric Society 1992;35(6):769-775.
Published online June 15, 1992.
Exercise Induced Delayed Bronchoconstriction in children with Asthma
Eun Jin Choi, Hyo Kung Shin, Un Ki Yoon, Ji Sub Oh
Department of Pediatrics, Wallace Memorial Baptist Hospital, Pusan, Korea
기관지 천식 환아에서 보인 운동 유발성 지연형 기관지 수축반응
최은진, 신효경, 윤운기, 오지섭
부산 왈레스 기념 침례회 병원 소아과
This study was performed to investigate delayed bronchoconstriction in 17 extrinsic asthmatic children with exercise induced asthma. Pulmonary function was monitored by PEFR and FEV1 prior to exercise and serially for ten hours after about 8 minutes up and down stairs exercise. Delayed bronchoconstriction was noted in four of seventeen patients (23.5%) at 5∼9hours after exercise and % fall in PEFR and FEV1 was less severe than that of the immediate bronchoconstriction. No significant differences were observed in the severity of immediate bronchoconstrition, baseline pulmonary function and IgE serum level between patients with single immediate and dual bronchoconstriction. But the rate of spontaneous recovery from the immediate bronchoconstriction was slower in patients with dual bronchoconstriction than that with single immediate constriction, suggesting that this variable may predict development of delayed bronchoconstriction in exercise induced astnma.
Key Words: Exercise induced asthma, Delayed bronchoconstriction

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