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Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy

Journal of the Korean Pediatric Society 1994;37(3):397-404.
Published online March 15, 1994.
Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy
Hye Young Kang1, Kook In Park1, Ran Namgung1, Chul Lee1, Chang Jun Coe1, Dong Gwan Han1, Tae Sub Chung2, Woo Hee Jung3
1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea
2Department of Diagnostic Radiology, College of Medicine, Yonsei University, Seoul, Korea
3Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea
신생아 경련이 동반된 대뇌 반측 위축 환아에 있어서 Tc-99m HMPAO SPECT 소견
강혜영1, 박국인1, 남궁란1, 이철1, 고창준1, 한동관1, 정태섭2, 정우희3
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 방사선과학교실
3연세대학교 의과대학 소아과학교실
Abstract
Functional brain imaging is very important in the diagnosis and evaluation of the various neurologic disorders. In addition to electroencephalography (EEG) and positron emission tomography (PET), single photon emission computed tomography (SPECT) have increasingly gained importance in determination of disturbances in regional brain functions. Both ictal and interictal Tc-99m hexamethyl-propyleneamine oxime single photon emission computed tomography (Tc-99m HMPAO SPECT) was done in a patient with the neonatal seizure and right cerebral hemiatrophy. The left parieto-occipital area revealed increased radioactivity during ictal stage and decreased radioactivities during interictal stage on Tc-99m HMPAO Brain SPECT. This brain area was thought to be a epileptogenic focus. Ictal and interictal Tc-99m HMPAO brain SPECT could be a safe and sensitive diagnostic method in localization of epileptogenic foci.
Key Words: Functional brain imaging, Tc-99m HMPAO brain SPECT, Epileptogenic focus


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