| Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children |
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Sei Ho Oh1, Young Ah Lee1, Woong Young Moon1, Tae Sun Won1, Young Seo Park1, Hyung Nam Moon1, Chang Yee Hong1, Dae Won Kim2 |
1Department of Pediatrics, College of Medicine University of Ulsan, Seoul, Korea
2Department of Clinical Pathology, College of Medicine University of Ulsan, Seoul, Korea |
| 한국 소아에서의 Epstein-Barr Virus (EBV)항체가에 관한 연구 |
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오세호1, 이영아1, 문웅영1, 고태성1, 박영서1, 문형남1, 홍창의1, 김대원2 |
1울산대학교 의과대학 소아과학교실
2울산대학교 의과대학 임상병리과학교실 |
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| Abstract |
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Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15 years old.
And the results were as follows;
1) The positive rates of anti-VCA IgG 100% in newborn, 90% in 2 to 6 months, 20% in 7 to 12 months, 60% in 1 to 2 years, 77.3% in 3 to 4 years, 88.5% in 5 to 6 years, 90% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively.
2) The anti-VCA IgG titers ranged from 1:20 to 1:1280
3) The positive rates of anti-EBNA were 100% in newborn, 60% in 2 to 6 months, 10% in 7 to 12 months, 60% in 1 to 2 years, 68.2% in 3 to 4 years, 84.5% in 5 to 6 years, 70% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively.
4) The anti-EBNA titers ranged from 1:2 to 1:128.
According to these data, the age of primary infection of EBV has increased compared to the previous data in Korean children. |
| Key Words:
Epstein-Barr virus, Antibody, Korean children |
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