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Neurosonographic Abnormality; Periventricular echodensities and Intraventricular Hemorrhage: Usefulness in Predicting Neurodevelopmental Outcome in Very-Low-Birth-Weight, Preterm Infants

Journal of the Korean Pediatric Society 1994;37(10):1376-1385.
Published online October 15, 1994.
Neurosonographic Abnormality; Periventricular echodensities and Intraventricular Hemorrhage: Usefulness in Predicting Neurodevelopmental Outcome in Very-Low-Birth-Weight, Preterm Infants
Dae Young Jang1, Keun Wook Lee1, Young Taek Jang1, Oh Kyung Lee1, Jin Ok Choi1, Yeon Hi Kim2
1Department of Radiology, Presbyterian Medical Center, Chon Ju, Korea
2Department of Rahabilitation Medicine, Presbyterian Medical Center, Chon Ju, Korea
극소 저출생 체중아에서 뇌초음파 소견과 신경학적 장애와의 관계
장대영1, 이근욱1, 장영택1, 이오경1, 최진옥1, 김연희2
1전주예수병원 소아과
2전주예수병원 재활의학과
Abstract
Serial neurosonographic examinations are routinely performed at frequent intervals during nursery couse of all preterm infants of very low-birth-weight who are admitted to the intensive care nursery of Presbyterian Medical Center from November 1,1900 to July 30, 1992. After discharge, the following survivors who had received periodic, serial scanning by means of cranial ultrasonography were longitudinally observed in an interdisciplinary neurodevelopmental follow-up grogram to mean corrected age of 13 months. Neurodevelopmental outcome was assessed by means of Vojta's postural reaction and other neurological examinations. The results are as follows: 1) The incidence of PV-IVH in the study was 79%. 2) According to Papile뭩 grading system of PV-IVH, grade I was 22%, grade II was 46%, grade III was 19%, and grade IV was 13%. 3) The risk factors associated with PV-IVH were birth weight, gestational age, apgar score, ventilator care, RDS, and sepsis. 4) The mortality of PV-IVH was 20% for grade I, 19% for grade II, 44% for grade III, and 67% for grade IV. 5) According to relationship between PV-IVH and neurodevelopmental outcome, in two of the four subjects with grade III PV-IVH, moderate/severe CCD was developed. 6) According to relationship betwwen PVE with cysts and nuerodevelopmental outcome, moderate/severe PVE with periventricular cysts larger than 3 mm in diameter was associated with development of severe CCD.
Key Words: Periventricular-intraventricular hemorrhage, Very low birth weight, Cranial ultrasonography


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