| Epidemiologic Study of Measles Outbreak in School-Aged Children in East KyongGi-Do Area |
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In Kyu Yi1, Jong Woon Choi1, Soon Ki Kim1, Byong Kwan Son1, Jeung Gyu Kim1, Seong Ki Yu2, Myung Cheol Joe3, Il Suk Jang4 |
1Department of Pediatrics, College of Medicine, InhaUniversity, InhaHospital, Seongnam,Kore
2Yu`s Pediatric Clinic
3Jo`s Pediatric Clinic
4Jang`s Pediatric Clinic |
| 성남, 광주, 이천지역의 국민학교 아동을 대상으로 한 홍역 예방접종 실태 및 효능에 관한 역학조사 |
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이인규1, 최종운1, 김순기1, 손병관1, 김정규1, 유성기2, 조명철3, 장일석4 |
1인하대학교 의과대학 소아과학교실
2유성기 소아과
3조명철 소아과
4장일석 소아과 |
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| Abstract |
Purpose
: There was marked decline of measles outbreak in the world since the first measles vaccine had been introduced. Recently, however, measles outbreak in the vaccinated children have been reported worldwide, which was ascribed to the possibilities of primary or secondary vaccine failure. We investigated the incidence in the school-aged children in the Kyong-gi Do area, the larger district which covers the urban and rural area, by the questionnaire.
Methods
: The questionnaires which were asked to the students' parents of 14 elementary schools in and nearest Sungnam city, Kyong-Gi Do for their present age, experience of measles attack and vaccination, and the age of measles attack. The answers of this questionnaire were analysed by SAS computer program.
Results
: 1) Measles vaccination rate at 9 months was 70.5% and MMR vaccination rate at 15 months was 91.3%.
2) Measles attack rate among unvaccinated group was 53.8%, and 16.1% in vaccinated group. There was significant low risk of measles attack among vaccinated group than unvaccinated group(relative risk=3.35, p<0.001).
3) Vaccine efficacy of measles in this age group was 69%.
4) Age distribution of measles outbreak reveals bimodal pattern, the graph shows two peak incidence of 1 year-old and 6 years-old.
5) There were no significant differences of measles incidence in the different medical care service center that measles vaccination had been done.
Conclusion
: Despite high rate of measles vaccine coverage in Sungnam, the attack rate of measles in the vaccinated population was relatively high. There may be due to primary, secondary vaccine failure or the other factors. The policy of measles vaccination in Korea should be reestablished as soon as possible. |
| Key Words:
Measles, Vaccine efficacy, MMR Vaccine |
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