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Three Cases of Cardiac Arrythmias Associated with Intravenous Methylprednisolone Pulse Therapy

Journal of the Korean Pediatric Society 1997;40(3):393-407.
Published online March 15, 1997.
Three Cases of Cardiac Arrythmias Associated with Intravenous Methylprednisolone Pulse Therapy
Jun Ho Lee, Jun Huh, Myung Dong Shin, Dong Kyu Jin, Il Soo Ha, Hae Il Cheong, Chung Il Noh, Yong Choi
Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
Methylprednisolone Pulse Therapy로 초래된 심부정맥 3례
이준호, 허준, 신명동, 진동규, 하일수, 정해일, 노정일, 최용
서울대학교 의과대학 소아과학교실
Abstract
Methylprednisolone(MP) is administered by means of intravenous pulse therapy especially in the patients with focal segmental glomerulosclerosis(FSGS). There have been reports of its complications in a few increasing frequency. We experienced three cases of cardiaccomplications during intravenous pulsetherapy.Therewere onecaseof2¡ÆA-V block(Mobitztype I) and two cases of bradycardia and hypotension. In the former,2¡ÆA-V block in the first case deveoloped 45 hours after MP infusion and subsided subsequently but reappeared athis EKG checked after 4 months. All of these complications resolved spontaneously. We should be awared of the fact that arrythmia resulting from MP infusion can be fetal.Therefore when IMPT are attempted, we should keep in mind of emergency life-saving preparations at bedside.
Key Words: Methylprednisolone, Arrhythmia


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