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A Case of Candida Endocarditis with Vegetation on the Tricuspid Valve in a Preterm Infant

Journal of the Korean Pediatric Society 2000;43(6):832-836.
Published online June 15, 2000.
A Case of Candida Endocarditis with Vegetation on the Tricuspid Valve in a Preterm Infant
Hye Young Han1, Mi Jin Jung1, Kwang Hoon Lee1, Gil Hyun Kim1, Hak Soo Lee1, Guk Yang Park2, Young Ha Oh3
1Department of Pediatrics, Gachon Medical School, Inchon, Korea
2Department of Cardiovascular Surgery, Gachon Medical School, Inchon, Korea
3Department of Anatomical Pathology, Gachon Medical School, Inchon, Korea
조산아에서 삼첨판막의 증식조직을 보인 칸디다성 심내막염 1례 - 수술적 제거 및 항진균제 치료의 성공적 치험 -
한혜영1, 정미진1, 이광훈1, 김길현1, 이학수1, 박국양2, 오영하3
1가천의과대학 소아과학교실
2가천의과대학 흉부외과학교실
3가천의과대학 해부병리과학교실
Abstract
Fungal endocarditis is a rare disease in infants, but it has been reported with increasing frequency among premature infants requiring neonatal intensive care. Congenital heart disease, prolonged intravenous catheterization, the use of intravenous alimentation, broad-spectrum antibiotics administration and narcotic addiction are risk factors. Candida endocarditis is an unusual but severe complication of systemic candidiasis. Its occurrence has been related to the placement of a central venous catheter with its tip close to or within the right atrium and persistent candidemia. Embolization to major blood vessels is a common complication of Candida endocarditis and repeated pulmonary emboli are suspected to be cause of the repeated episodes of circulatory shock which finally leads to death. Thus, early diagnosis of Candida invasion and prevention of Candida endocarditis are essential for survival. We report a case of Candida endocarditis which was successfully managed with surgical removal and antifungal therapy.
Key Words: Candida endocarditis, Vegetation, Tricuspid valve


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