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A Case of Chronic Pneumonitis of Infancy in Pediatric Interstitial Lung Disease

Journal of the Korean Pediatric Society 2001;44(9):1085-1090.
Published online September 15, 2001.
A Case of Chronic Pneumonitis of Infancy in Pediatric Interstitial Lung Disease
Hyun Oh Jang, Se Chang Ham, Young Kyoun Kim, Se Wook Oh, Yong Won Park
Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea
간질성 폐질환에 속하는 만성 영아 폐렴 1례
장현오, 함세창, 김영균, 오세욱, 박용원
인제대학교 의과대학 소아과학교실
Correspondence: 
Se Chang Ham, Email: myallergydr@hotmail.com
Abstract
The interstitial lung diseases(ILD) comprises a large, heterogeneous group of disorders characterized by derangement of alveolar walls and alveolar capillary unit causing restrictive pulmonary dysfunction and disordered gas exchange. It is rare, especially in children, and the opinions on investigation and treatments are controversial. The classification of adult ILD is applied to that of children. But considering occurrence during the developing state of lung and immune systems, we should be more cautious because the clinical manifestations and prognosis will be different from those of adults. In 1995, Katzenstein named a unique type of ILD, chronic pneumonitis of infancy (CPI) for the first time. CPI is characterized by marked alveolar septal thickening, striking type II pneumocyte hyperplasia, and eosinophilic alveolar exudate containing numerous macrophages. We report a 14 month-old girl, who had continuing respiratory difficulty and cyanosis after upper respiratory infection, could not sustain oxygen saturation and was finally diagnosed as CPI by histologic examination.
Key Words: Interstitial lung disease, Chronic pneumonitis of infancy, Children


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