Diagnostic Value of 99mTc-DMSA Pinhole Imaging in Childhood Urinary Tract Infection with Renal Cortical Defect |
Tae Won Lee1, Seung Jun Seong1, Byung Moon Ahn1, Ie Ryung Yoo2, Il Soo Kim1, Eun Ryoung Kim1, Sung Hoon Kim2, Yong-Whee Bahk3 |
1Departments of Pediatric, Sung-Ae General Hospital, Seoul, Korea 1Departments of Pediatric, Sung-Ae General Hospital, Seoul, Korea 2Department of Nuclear Medicine, Kangnam St. Mary`s Hospital, Catholic University M edical School, Seoul, Korea 3Departments of Nuclear Medicine, Sung-Ae General Hospital, Seoul, Korea |
요로감염에서 99mTc-DMSA Pinhole 영상의 유용성 |
이태원1, 성승준1, 안병문1, 유이령2, 김일수1, 김은령1, 김성훈2, 박용휘3 |
1성애병원 소아과 1성애병원 소아과 2강남성모병원 핵의학과 3성애병원 핵의학과 |
Correspondence:
Eun Ryoung Kim, Email: NICU@chollian.net |
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Abstract |
Purpose : The aim of this study was to assess the diagnostic value of the 99mTc-DMSA pinhole
imaging by comparing the detection rate of cortical defects identified from planar and pinhole
imaging.
Methods : 99mTc-DMSA planar and pinhole imaging, voiding cystoureth-rogram(VCUG), renal ultrasonography
were performed in 67 patients diagnosed with urinary tract infection at the Department
of Pediatrics, Sung-Ae General Hospital, from September, 1999 to Feburary, 2001. The
follow-up of 99mTc-DMSA pinhole imaging was performed on 25 patients.
Results : Overall detection rate of 99mTc-DMSA planar imaging was 41.8%(28 patients/67 patients),
but 99mTc-DMSA pinhole imaging showed cortical defects in 62.7%(42 patients/67 patients)
and the patients with renal cortical defects in planar imaging showed all definite or more
additional cortical defects in pinhole imaging. The detection rate of cortical defect by 99mTc-
DMSA pinhole imaging in patients with vesicoureteral reflux(VUR) was 80%(24 kidneys/30
kidneys). Those without VUR, however, also presented high detection rate as 25.9%(27 kidneys/
104 kidneys). Out of 25 patients, improvement of cortical defect was presented in 19, no change
in 4, and aggravation in 2 from the follow-up studies by 99mTc-DMSA pinhole imaging.
Conclusion : This study indicates that 99mTc-DMSA pinhole imaging is superior to planar imaging
and, hence, that pinhole imaging is a useful initial diagnostic tool for children suspected of
urinary tract infection, irrespective of VUR, and to identify patients who need more extensive
radiological studies and early treatment. |
Key Words:
99mTc-DMSA, Pinhole, Planar, Urinary tract infection |
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