| A Successful Transplant of HLA-3 Loci
Mismatched Umbilical Cord Blood into a Patient with
Acute Myeloid Leukemia from an Unrelated Donor |
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Byoung Chul Kwon1, Kyung Mi Shin1, Sung Chul Won1, Chuhl Joo Lyu1, Chang Hyun Yang1, Hyun Ok Kim2 |
1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea
2Department of Clinical Pathology, College of Medicine, Yonsei University, Seoul, Korea |
| 급성 골수구성 백혈병 환아에서 비혈연간 주조직 적합항원 3부위 불일치 제대혈 조혈모세포 이식 성공 1례 |
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권병철1, 신경미1, 원성철1, 유철주1, 양창현1, 김현옥2 |
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 임상병리학교실 |
Correspondence:
Chuhl Joo Lyu, Email: cj@yumc.yonsei.ac.kr
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| Abstract |
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Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and the platelet recovered greater than 20,000/mm3 independent of transfusion at day 81 after stem cell infusion. |
| Key Words:
Cord blood transplantation, HLA-3 loci mismatching, Unrelated donor |
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