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A Case of Mycoplasma pneumoniae Pneumonia Complicated with Guillain-Barr Syndrome and Encephalitis

Korean Journal of Pediatrics 2004;47(12):1338-1348.
Published online December 15, 2004.
A Case of Mycoplasma pneumoniae Pneumonia Complicated with Guillain-Barr Syndrome and Encephalitis
Soon Bum Lee1, Hee Jung2, Yong Seok Lee2, Bum Sun Kwon3, Jeesuk Yu1
1Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea
2Department ofDiagnostic Radiology, College of Medicine, Dankook University, Cheonan, Korea
3Department of Rehabilitation, College of Medicine, Dankook University, Cheonan, Korea
Mycoplasma pneumoniae 폐렴에 병발한 Guillain-Barr 증후군 및 뇌염 1례
이순범1, 정은희2, 이영석2, 권범선3, 유지숙1
1단국대학교 의과대학 소아과학교실
2단국대학교 의과대학 진단방사선과학교실
3단국대학교 의과대학 재활의학교실
Correspondence: 
Jeesuk Yu, Email: dryujs@dankook.ac.kr
Abstract
The most common pathogen of respiratory tract infection among school-age children and adolescents is Mycoplasma pneumoniae, which causes clinical manifestations of pneumonia, acute asthmatic attack, pharygitis, and tonsilitis. It can also cause extrapulmonary infections that involves skin, the nervous system, the digestive system, the cardiovascular system, and the hematopoietic system. It is reported that the central nervous system symptoms may occur in 0.1% to 7% of patients hospitalized with Mycoplasma pneumoniae infection. Direct invasion, toxin, immune-mediated, and vascular phenomenon have been proposed for the etiology of the neurological manifestations. We have experienced a six-year-old male patient with Mycoplasma pneumoniae pneumonia who had complained of both leg pains and immobility two weeks after the onset of pneumonia, which was confirmed as peripheral neuropathy of Guillain-Barr syndrome. Three weeks after the disease-onset, altered consciousness and seizure attacks developed and intravenous immunoglobulins infused under the impression of encephalitis induced by Mycoplasma pneumoniae infection. He showed complete recovery of running and mentality five months after the disease-onset. We herein report a case of Mycoplasma pneumoniae pneumonia complicated with Guillain-Barr Syndrome and encephalitis about 2 or 3 weeks after the disease onset with a review of literatures.
Key Words: Pneumonia, Mycoplasma, Guillain-Barr syndrome, Encephalitis, Immunoglobulins


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