A Case of Neonatal Lupus Erythematosus Associated with Anti-U1RNP Antibodies |
Byung-Hoon Ahn1, Gu Chang Lee2, Tae Young Yoon2, Mi-Jung Kim1 |
1Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea 2Department of Dermatology & Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Korea |
항-U1RNP 항체 양성인 신생아 홍반성 루푸스 1례 |
안병훈1, 이구창2, 윤태영2, 김미정1 |
1충북대학교 의과대학 소아과학교실 2충북대학교 의과대학 피부과학교실 & 의학연구소 |
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Abstract |
Neonatal lupus erythematosus(NLE) is a distinct subset of lupus characterized by cutaneous findings, cardiac conduction defects, hepatic or hematologic abnormalities. These manifestations are associated with the presence of maternal auto-antibodies such as anti-SSA/Ro, anti-SSB/La, and rarely anti- RNP(U1RNP) antibodies. Cases of U1RNP antibody-positive NLE have somewhat atypical cutaneous manifestation without cardiac or systemic abnormalities. We report a case of cutaneous NLE associated with U1RNP antibodies. |
Key Words:
Neonatal lupus erythematosus , U1RNP antibody |
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