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Prevention and Dissociation of the Platelet Aggregation in a Patient with EDTA-dependent Pseudothrombocytopenia by Supplementation of Kanamycin : A Case Report

Korean Journal of Pediatrics 2005;48(6):675-677.
Published online June 15, 2005.
Prevention and Dissociation of the Platelet Aggregation in a Patient with EDTA-dependent Pseudothrombocytopenia by Supplementation of Kanamycin : A Case Report
In-sang Jeon, Sung Wan Yang
Department of Pediatrics, Gachon Medical School, Incheon, Korea
EDTA 의존성 가성혈소판감소증 환아에서 가나마이신 보충에 의해 혈소판 응집을 예방할 수 있었던 1례
전인상, 양성완
가천의과대학교 소아과학교실
Correspondence: 
In-sang Jeon, Email: isjeon@ghil.com
Abstract
Pseudothrombocytopenia is usually associated with anticoagulant ethylene diaminetetraacetic acid (EDTA). The platelet clumping that occurs in EDTA-dependent pseudothrombocytopenia (EDPT) can sometimes be prevented by the use of other anticoagulants such as heparin or sodium citrate. As an alternative, we used kanamycin before or after the withdrawal of EDTA-anticoagulated blood in a 6-year-old boy with EDPT. Kanamycin used supplementarily during the differentiation of EDPT effectively prevented platelet clumping.
Key Words: Pseudothrombocytopenia , EDTA , Kanamycin


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