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Birth Weight Distribution by Gestational Age in Korean Population : Using Finite Mixture Modle

Korean Journal of Pediatrics 2005;48(11):1179-1186.
Published online November 15, 2005.
Birth Weight Distribution by Gestational Age in Korean Population : Using Finite Mixture Modle
Jung-Ju Lee1, Chang Gi Park2, Kwang-Sun Lee2
1Department of Pediatrics, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea
2Section of Neonatology, Department of Pediatrics, University of Chicago, USA
우리나라 신생아의 재태 연령에 따른 출생체중의 정상치 : Finite Mixture Model을 이용하여
이정주1, 박창기2, 이광선2
1울산대학교 의과대학 강릉아산병원 소아과
2시카고대학병원 소아과
Correspondence: 
Jung-Ju Lee, Email: neoljj@gnah.co.kr
Abstract
Purpose
: A universal standard of the birth weight for gestational age cannot be made since girth weight distribution varies with race and other sociodemographic factors. This report aims to establish the birth weight distribution curve by gestational age, specific for Korean live births.
Methods
: We used the national birth certificate data of all live births in Korea from January 2001 to December 2003; for live births with gestational ages 24 weeks to 44 weeks(n=1,509,763), we obtained mean birth weigh, standard deviation and 10th, 25th, 50th, 75th and 90th percentile values for each gestational age group by one week increment. Then, we investigated the birth weight distribution of each gestational age group by the normal Gaussian model. To establish final standard values of Korean birth weight distribution by gestational age, we used the finite mixture model to eliminate erroneous birth slights for respective gestational ages.
Results
: For gestational ages 28 weeks 32 weeks, birth weight distribution showed a biologically implausible skewed tail or bimodal distribution. Following correction of the erroneous distribution by using the finite mixture model, the constructed curve of birth weight distribution was compared to those of other studies. The Korean birth weight percentile values were generally lower than those for Norwegians and North Americans, particularly after 37 weeks of gestation. The Korean curve was similar to that of Lubchenco both 50th and 90th percentiles, but generally the Korean curve had higher 10th percentile values.
Conclusion
: This birth weight distribution curve by gestational age is based on the most recent and the national population data compared to previous studies in Korea. We hope that for Korean infants, this curve will help clinicians in defining and managing the large for gestational age infants and also for infants with intrauterine growth retardation.
Key Words: Birth weight , Gestational age , Finite mixture model


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