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Recent outcome of extremely low birth weight infants - The use of CRIB(clinical risk index for babies) Ⅱ score foranalyzing the survival rate -

Korean Journal of Pediatrics 2006;49(9):952-958.
Published online September 15, 2006.
Recent outcome of extremely low birth weight infants - The use of CRIB(clinical risk index for babies) Ⅱ score foranalyzing the survival rate -
Do-Hyeon Kim1, So-Yeon Shim2, Jae-Ri Kim1, Seung-Han Shin1, Eun Sun Kim1, Kyoung-Eun Joung1, Sang Duk Kim1, Jin A Lee3, Chang Won Choi1, Ee-Kyung Kim1, Han-Suk Kim1, Beyong Il Kim1, Jung-Hwan Choi1
1Departments of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
2Department of Pediatrics, Gil Medical Center, Gacheon Medical School, Incheon, Korea
3Department of Pediatrics, Boramae Hospital, Seoul National University, Seoul, Korea
초극소 저출생 체중아의 최근 치료 성적 - CRIB(clinical risk index for babies) Ⅱ 점수를 이용한 생존율 분석 -
김도현1, 심소연2, 김재리1, 신승한1, 김은선1, 정경은1, 김상덕1, 이진아3, 최창원1, 김이경1, 김한석1, 김병일1, 최중환1
1서울대학교 의과대학 소아과학교실
2가천의과대학교 길병원 소아과
3서울대학교 보라매병원 소아과
Correspondence: 
Jung-Hwan Choi, Email: neona@plaza.snu.ac.kr
Abstract
Purpose
: The survival rate of infants weighing less than 1,000 g at birth(extremely low birth weight infants, ELBWI) has increased due to recent advances in perinatal and neonatal intensive care. The purpose of this study was to evaluate the survival rates of ELBWI born at Seoul National University Hospital during the last six years.
Methods
: A total of 99 infants were divided into three groups(period Ⅰ: 2000 to 2001, period Ⅱ: 2002 to 2003, period Ⅲ : 2004 to 2005) based on date of birth. We compared the survival rate of ELBWI over the three periods, using CRIB Ⅱ score for adjustment for clinical severity.
Results
: Overall survival rate of ELBWI was 74.7 percent. The survival rate of ELBWI increased over the three periods(period Ⅰ: 60.7 percent, period Ⅱ : 73.3 percent, period Ⅲ : 85.3 percent). The threshold of viability(defined as survival of at least 50 percent of infants) was 25 weeks of gestation and 600 g at birth. The birth weight-specific survival rates increased considerably over the three periods for infants <750 g at birth(period Ⅰ: 10 percent, period Ⅱ: 46.2 percent, period Ⅲ : 70.6 percent). The survival rates of ELBWI over the three periods increased much remarkably after adjustment for clinical severity by CRIB Ⅱ score.
Conclusion
: In our institution, survival rates of ELBWI during the last six years continued to improve, particularly for infants weighing <750 g at birth. This increase in survival rates was not associated with the clinical severity of ELBWI.
Key Words: Extremely low birth weight infant , Survival rate , CRIB Ⅱ score


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