Palliative effect of 131I-MIBG in relapsed neuroblastoma
after autologous peripheral blood stem cell transplantation |
Yong Jik Lee, Jeong Ok Hah |
Department of Hematology/Oncology, Yeungnam University College of Medicine |
자가 말초혈조혈모세포이식 후 재발된 신경모세포종 3예에서 131I-MIBG의 고식적 치료 효과 |
이용직, 하정옥 |
영남대학교 의과대학 소아과학교실 |
Correspondence:
Jeong Ok Hah, Email: johah@med.yu.ac.kr |
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Abstract |
Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine (131I-MIBG) therapy is an alternative approach to treat stage Ⅳ neuroblastoma. We report the palliative effect of 131I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. 131I-MIBG is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival. |
Key Words:
Relapsed neuroblastoma, 131I-MIBG, Palliative therapy |