| Pi phenotyping in cord blood of 543 newborns. |
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Mee Na Lee1, Jong Su Chun2, Soo Kyung Choi3, Yong Kyun Paik3 |
1Department of Pediatrics, Cheil General Hospital, Seoul Korea
2Department of Obstetrics & Gynecology, Cheil General Hospital, Seoul Korea
3Genetics Research Laboratory, Cheil General Hospital, Seoul Korea |
| 신생아 543명의 제대혈에서 시행한 Pi Phenotyping |
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이미나1, 전종수2, 최수경3, 백용균3 |
1제일병원 소아과
2제일병원 산부인과
3제일병원 유전학연구실 |
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Received: 31 January 1991 • Accepted: 7 February 1991 |
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| Abstract |
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Phenotypes and • gene frequencies in cord blood samples of 543 newborns were studied for Pi
phenotypes for the purpose of estimating the risk of diseases associated with genetic deficiency of
alpha-1 antitrypsin. Pi phenotypes were performed by polyacrylamide gel separator isoelectric
focusing method. The allele frequencies obtained were as follows:'PiM!=0.7670, M2=0.1796 M3=0.
0506, G=0.0018,/P=0.0009. There were no alleles causing severe deficiency such as Z or S, and there
was no significant difference compared to normal adult populations. |
| Key Words:
Phenotypes, allels frequencies |
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