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A Case of Malignant Ependymoma.

Journal of the Korean Pediatric Society 1989;32(1):130-136.
Published online January 31, 1989.
A Case of Malignant Ependymoma.
Ja Wook Koo, Sun Ho Lee, In Joon Seol, Hahng Lee
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea
영아기에 발생한 악성상의세포종 1례
구자욱, 이선호, 설인준, 이항
한양대학교 의과대학 소아과학교실
Received: 2 May 1988   • Accepted: 15 July 1988
Intracranial tumors presenting in the first year of life are uncommon. Brain tumors in infancy are predominantly supratentorial, whereas in older children the majority are infratentorial. Malignant ependymoma is a rare type of primitive ependymal tumor with clinically high malignancy. We experienced a malignant ependymoma in a 5 month old girl who had progressive enlargement of head circumference with vomiting. Brain computed tomography revealed a 10 x 10 cm sized mass in left parietotemporal area of the cerebral hemisphere with multiple punctate calcifications along the outer margin of the mass. Diagnosis was confirmed by histologic examination of the tumor tissue On microscopic examination the tumor was well circumscribed and fairly cellular. The tumor cells were polygonal or elongated with regular round nuclei and delicate chromatin pattern. In areas perivascular pseudorosette as well as numerous mitoses and multifocal necrosis were presented. We present a case of malignant ependymoma with the brief review of related literatures.
Key Words: Malignant ependymoma

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